There are many places to get into trouble in Karnak.
The Lakes (east of Carclew)
The Watch Tower is located through the pass at (59,53) and stands at (63,49). This mysterious sentinel guards an ancient burial mound wherein is located the Lay of Victory and Ossian's tomb. Although this is inaccessible for some time, it is important to trigger the Watch Tower.
A nest of spiders live at (55,46)
Tin Mine at (48,71) is infested with vicious rock creatures. Clear them out and the tinners in Ryn will be very grateful. Once peace with the Runics is declared the tinners can set up trade routes to cement their relationship with the Runics.
Shipwreck at (50,86) this ill fated ship was carrying some mysterious cargo hinted at by the captain's log. Like any good sailor upon crashing he immediately crawled to the nearest cave and buried some treasure and of course drew a map. Although its supposed to be a veiled joke, the cargo that the captain describes is very important and can be found in Skullkeep.
Cave network (41,85) the captain's body is inside the cave at (17,82) with a map to the treasure buried at (34,74). Unfortunately Reef Grimals inhabit the place.
Greyclaw lives at 59,74. He is very friendly but not particularly useful. However, if the party destroys the statue (55,74) of his dead wife, his daughter, a werebear will attack them. If Greyclaw smells his daughters blood upon you he too will convert to bear form and attack.
Ardon the Leper lives at (85,87). He has some vague but somewhat useful information. He wants the Horn of the Wild Hunt, possessed by the Horned Hunter. For it he will trade a book enhancing intelligence. To reach the Horned Hunter the party will need Teague's Helm of Silence which is in the treasure horde of the Earth Dragon (see the Laerg). If he receives the Horn Ardon will disappear, but before he does there will be a hint about his true natue (if you know your celtic myths you might pick up on it - its not vital to the plot though).
Llywarch the Bard lives at (63,84). He is under the spell of a strange fey creature that lives off of the inherent magic of Bards. He is forced to play endlessly for the amusement of this creature. The party is unable to intervene until Rowan tells them to find Llywarch and ask him where to find Ossian's Lay of Victory.
An encounter with a group of bandits in the forest around (81,74) will uncover a coded message on the body of a victim. This is the beginning of another major subplot - Manannan's Quest.